Technology

Posters

Oral Presentation given to the American Association for Cancer Research (AACR) Annual Meeting 2024

Preliminary clinical results of a therapeutic cancer vaccine PDC*lung01 in combination with anti-PD-1 in patients with Stage IV NSCLC

 

W. Theelen, M. Perol, K. Cuppens, I. Demedts, F. Borm, B. Biesma, E. Wauters, B. Colinet, E.-L. Buchmeier, F. Althoff, E. Pons-Tostivint, C. Van de Kerkhove, D. Moro-Sibilot, A. Sibille, S. Derijcke, M. Skrzypski, J. Plumas, B. De Vos, C. Debruyne, F. Cantero, S. Adriaenssens, F. Renard, J. Vansteenkiste;

 

Presented April 7, 2024

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Poster presented to AACR Annual Meeting 2024

PDC*lung01: An innovative therapeutic cancer vaccine induces specific immune responses in combination with anti-PD-1 treatment in patients with non-small cell lung cancer

J. Plumas, A. Sibille, I. Demedts, E. Pons-Tostivint, C. Van de Kerkhove, S. Derijcke, W. Theelen, B. Biesma, F. Borm, E. Wauters, M. Collodoro, K. Al Badawy, C. Duchayne, C. Debruyne, B. De Vos, B. Colinet, D. Moro-Sibilot, M. Perol, E. Buchmeier, M. Skrzypski, K. Cuppens, J. Vansteenkiste

Presented April 7, 2024

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Oral Presentation given to the 49th annual meeting of the Korean Cancer Association & 9th international Cancer Conference

A new plasmacytoid dendritic cell-based vaccine in combination with anti-PD-1 expands tumor-specific CD8+ T cells of lung cancer patients

S-E. Kim, D. Hannani, E. Leplus, D. Laurin, B. Caulier, C. Aspord, N. Madelon, E. Bourova-Flin, C. Brambilla, E. Brambilla, A-C. Toffart, K. Laulagnier, L. Chaperot, J. Plumas

Presented June 15, 2023

PLUMAS J_KCA 2023.pdf

 

Poster presented to 20th CIMT Annual Meeting 

Induction of circulating antitumor specific CD8+ T cells in patients with non-small cell lung cancer treated with an allogeneic plasmacytoid dendritic-cell based cancer vaccine with or without anti- PD-1 treatment
S. Michel, I. Demedts, A. Sibille, E. Pons-Tostivint, C. Van de Kerkhove, S. Derijcke, M. Collodoro, K. Al Badawy, C. Duchayne, C. Debruyne, M. Perol, E.-L. Buchmeier, K. Cuppens, J. Vansteenkiste, J. Plumas

Presented May 5, 2023

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Poster presented to ESMO Iummuno-Oncology Congress 2022 

The therapeutic cancer vaccine PDC*lung01 induces immune responses with or without anti- PD-1 treatment in patients with non-small cell lung cancer
A. Sibille, J. Plumas, I. Demedts, E. Pons-Tostivint, C. Van de Kerkhove, S. Derijcke, M. Collodoro, K. Al Badawy, C. Duchayne, C. Debruyne, M. Pérol, E. Buchmeier, K. Cuppens, J. Vansteenkiste

Presented December 8, 2022
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Poster presented to ESMO 2022 Annual Meeting

Open-label, dose-escalation, phase I/II study to assess the safety, tolerability, immunogenicity and preliminary clinical activity of the therapeutic cancer vaccine PDC*lung01 with or without anti-Programmed Death-1 (PD-1) treatment in patients with non-small-cell lung cancer (NSCLC).
J. Vansteenkiste, I. Demedts, E. Pons-Tostivint, B. Biesma, F. Borm, B. Colinet, K. Cuppens, S. Derijcke, L. Greillier, J. Jurgens, D. Moro-Sibilot, M. Pérol, M. Sebastian, M. Skrzypski, W. Theelen, C. Van De Kerkhove, M. Collodoro, J. Plumas, C. Debruyne, A. Sibille

Presented September 12, 2022
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eTalk given to the 18th CIMT Annual Meeting

Priming and expansion of functional antitumor T-cells in melanoma patients: results of phase I clinical trial with GeniusVac-Mel4, an innovative cancer vaccine based on a plasmacytoid dendritic cell line.
J. Charles, L. Chaperot, D. Hannani, J. Bruder Costa, I. Templier, S. Trabelsi, H. Gil, A. Moisan, V. Persoons, H. Hegelhofer, E. Schir, J.-L. Quesada, C. Mendoza, C. Aspord, O. Manches, P. Coulie, A. Khammari, B. Dreno, M.-T. Leccia, J. Plumas.

Presented: May 10-12, 2022
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eTalk given to the 18th CIMT Annual Meeting

The retroviral engineering of a human plasmacytoid dendritic cell-based vaccine allowed the priming and expansion of multispecific viral and tumor antigen-specific T-cells in multiple HLA contexts.
K. Lenogue, A. Walencik, K. Laulagnier, J.-P. Molens, H. Benlalam, B. Dreno, P. Coulie, M. Pule, L. Chaperot, J. Plumas

Presented: May 10-12, 2022
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Poster presented to ESMO Iummuno-Oncology Congress 2022 

The therapeutic cancer vaccine PDC*lung01 induces immune responses with or without anti- PD-1 treatment in patients with non-small cell lung cancer
A. Sibille, J. Plumas, I. Demedts, E. Pons-Tostivint, C. Van de Kerkhove, S. Derijcke, M. Collodoro, K. Al Badawy, C. Duchayne, C. Debruyne, M. Pérol, E. Buchmeier, K. Cuppens, J. Vansteenkiste

Presented December 8, 2022
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Poster presented to ESMO 2022 Annual Meeting

Open-label, dose-escalation, phase I/II study to assess the safety, tolerability, immunogenicity and preliminary clinical activity of the therapeutic cancer vaccine PDC*lung01 with or without anti-Programmed Death-1 (PD-1) treatment in patients with non-small-cell lung cancer (NSCLC).
J. Vansteenkiste, I. Demedts, E. Pons-Tostivint, B. Biesma, F. Borm, B. Colinet, K. Cuppens, S. Derijcke, L. Greillier, J. Jurgens, D. Moro-Sibilot, M. Pérol, M. Sebastian, M. Skrzypski, W. Theelen, C. Van De Kerkhove, M. Collodoro, J. Plumas, C. Debruyne, A. Sibille

Presented September 12, 2022
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eTalk given to the 18th CIMT Annual Meeting

Priming and expansion of functional antitumor T-cells in melanoma patients: results of phase I clinical trial with GeniusVac-Mel4, an innovative cancer vaccine based on a plasmacytoid dendritic cell line.
J. Charles, L. Chaperot, D. Hannani, J. Bruder Costa, I. Templier, S. Trabelsi, H. Gil, A. Moisan, V. Persoons, H. Hegelhofer, E. Schir, J.-L. Quesada, C. Mendoza, C. Aspord, O. Manches, P. Coulie, A. Khammari, B. Dreno, M.-T. Leccia, J. Plumas.

Presented: May 10-12, 2022
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eTalk given to the 18th CIMT Annual Meeting

The retroviral engineering of a human plasmacytoid dendritic cell-based vaccine allowed the priming and expansion of multispecific viral and tumor antigen-specific T-cells in multiple HLA contexts.
K. Lenogue, A. Walencik, K. Laulagnier, J.-P. Molens, H. Benlalam, B. Dreno, P. Coulie, M. Pule, L. Chaperot, J. Plumas

Presented: May 10-12, 2022
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Poster presented to European Lung Cancer Virtual Congress (ELCC 2021 Virtual)

An open-label, dose escalation, Phase I/II study to assess safety, tolerability, immunogenicity and preliminary clinical activity of the therapeutic cancer vaccine PDC*lung01 with or without anti-Programmed Death-1 (PD-1) treatment in patients with Non-small cell lung cancer (NSCLC).
J. Bennouna, A. Sibille, C. Debruyne, B. Colinet, I. Demedts, S. Derijcke, L. Greillier, J. Jurgens, H. Lena, D. Moro-Sibilot, M. Pérol, X. Quantin, N. Reinmuth, M. Sebastian, M. Genin, J. Plumas, J. Vansteenkiste

Presented: March 25 – 27, 2021
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Poster presented to ESMO Immuno-Oncology Congress 2017

Priming and expansion of neo-antigen specific-T cells thanks to an off-the-self cell-based drug product.
Plumas J, De Sousa Alves PM, Leplus E, Chaperot L, Hannani D

December 7-10, 2017
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