A first in class Plasmacytoid Dendritic cell line, PDC*line providing unmatched advantages

  • Potent & effective

    Induction of a strong cytotoxic immune response directed against a selection of tumour antigens

  • Scalable & convenient

    Simple production of a large quantity of a highly qualified off-the-shelf vaccine

  • Versatile & applicable to any cancers

    The vaccine peptides can easily be changed to target a specific cancer type


PDC*line Pharma receives Advanced-Therapy Medicinal Product (ATMP) classification from the European Medicines Agency (EMA) for its new class of therapeutic cancer vaccines (PDC*vac) June 15th 2015 – The Philadelphia 2015Read more

Candidate products


Advanced stage


Melanoma is the most lethal form of skin cancer, representing 2% of all newly diagnosed cancer cases (232,000 new cases and 55,000 deaths worldwide in 2012). It is also the leading cancer in terms of incidence increase (+ 10% per year) and one of the most common cancers in young adults (18-35 years).

However, it is also more likely to spread (metastasize) to other parts of the body, and 16% of patients are first diagnosed at an advanced stage. Prognosis for this late-stage disease is very unfavorable (5-year mortality rate of 85%).



Lung Cancer,  Non-Small Cell,
Advanced stage


1.8 million new cases of lung cancer were diagnosed worldwide in 2012, and this disease was responsible for and 1.6 million deaths. Lung cancer is therefore the most frequently diagnosed cancer and the leading cause of cancer mortality.

About 40% of patients are diagnosed with locally advanced (stage IIIb) or metastatic (stage IV) cancer; prognosis is poor (median survival 8-13 months).


PDC*line Pharma


Founded in April 2014 in Grenoble (France) as a spin-off of the French Blood Bank (EFS), PDC*line Pharma is a clinical-stage biotech company that develops a new class of therapeutic cancer vaccines based on a line of Plasmacytoid Dendritic cells (PDC*line).

PDC*mel, our leading drug candidate is currently in phase 1 clinical trials for melanoma. PDC*lung is in preclinical development for lung cancer.

We aim to establish the clinical proof of concept for our technology, then negotiate an agreement with a pharmaceutical company and envisage to list the company on the stock exchange for further developments. about us